Challenges in the early detection and intervention of the psychosis-risk syndrome

概述

精神病临床高风险状态的概念已用于描述具有精神病前驱症状而处于高发病风险的个体。这一高风险概念促使人们更深入理解精神病的发展转归，并在为精神病临床高风险人群提供必要的精神卫生服务方面提供了理论依据。早期诊断和干预可能会改变精神病性状态的病程，从而防止相应功能损害的发生，或将功能损害减少到最小程度。这是相对较新的研究领域，需要更多的研究才能充分理解这种高风险状态。

中文全文

本文全文中文版从2015年4月8日起在http://dx.doi.org/10.11919/j.issn.1002-0829.215016可供免费阅览下载The concept of a clinical high-risk state for psychosis (HR) has recently gained popularity in clinical psychiatry as a means of describing individuals with prodromal psychotic symptoms who are at the cusp of developing a full-blown psychosis. Several labels have been used for this condition, including ‘psychosis risk syndrome’ (PRS), ‘prodromal psychosis’, or ‘very high-risk state’. Due to controversies around this concept, DSM-5 does not list HR as a diagnosis, but it does include ‘attenuated psychosis syndrome’ (APS) in the appendix as a condition worthy of further study. We believe use of the APS category can help in the early detection and intervention of psychotic disorders.