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Successful treatment of pulmonary mucormycosis in an allogenic bone-marrow transplant recipient with combined medical and surgical therapy
Authors:Pavie Juliette  Lafaurie Matthieu  Lacroix Claire  Marie Zagdanski Anne  Debrosse Denis  Socié Gérard  Derouin Francis  Gluckman Eliane  Michel Molina Jean
Institution:Service des Maladies Infectieuses et Tropicales, Paris, France.
Abstract:Mucormycosis is a rare, but severe, complication in allogenic bone-marrow recipients with a mortality rate of about 80%. Moreover, its incidence appears to have increased within the last decade. We report a case of pulmonary and nasal mucormycosis in a 55-y-old patient, which occurred 1 y after BMT. Treatment combining 4 months of amphotericin B, early surgical resection of infected tissue and discontinuation of immunosuppressive treatment allowed the cure of this mould infection.
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