Changes in body temperature markedly affect striatal dopamine release and metabolism: an in vivo study |
| |
| Authors: | T. Brannan J. Martínez-Tica M. D. Yahr |
| |
| Affiliation: | (1) Present address: Department of Neurology, Mount Sinai School of Medicine, New York, NY, USA |
| |
| Abstract: | Summary Dopamine release and metabolism in the corpus striatum increased markedly when the core body temperature of anesthetized rats was increased from 35 ° to 41 °C while temperatures below 34 ° were associated with a marked attenuation of dopamine release. These observations may have clinical relevance in cases where alterations in body temperature are associated with extrapyramidal dysfunction. |
| |
| Keywords: | Dopamine body temperature Parkinson's disease cerebral microdialysis |
| 本文献已被 SpringerLink 等数据库收录！ |
