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有氧运动对急性冠脉综合征患者血清黏附分子和C反应蛋白的影响
引用本文:史建俊,江山,刘毅,董小超.有氧运动对急性冠脉综合征患者血清黏附分子和C反应蛋白的影响[J].心脏杂志,2010,22(2):209-211.
作者姓名:史建俊  江山  刘毅  董小超
作者单位:1.青岛大学医学院心脏内科,山东 青岛266021;2.西京医院理疗科,5.西京医院心脏外科,4.第四军医大学病理生理学教研室,陕西 西安 710032;3.解放军401医院干部二科,山东 青岛 266071
基金项目:国家自然科学基金资助课题(30700965)
摘    要:目的: 探讨有氧运动对急性冠脉综合征(ACS)患者可溶性细胞间黏附分子-1(sICAM-1)、血管细胞黏附分子-1(sVCAM-1)和C反应蛋白(CRP)水平的影响。方法: 选取ACS患者70例,将其分为常规治疗组和有氧运动+常规治疗组(加有氧运动组)。另选健康成人为正常对照组。采用酶联免疫吸附法测定各组sICAM-1和sVCAM-1 水平,采用免疫浊度法测定CRP浓度。结果: ACS 患者循环血中sICAM-1、sVCAM-1和CRP水平明显高于正常对照组(P<0.01),两组治疗1个月后sICAM-1、sVCAM-1和CRP水平均较治疗前均明显下降(P<0.05和P<0.01)。且两组各项指标比较,加有氧运动组降低更显著(P<0.05)。结论: ACS 患者血清中sICAM-1、sVCAM-1和CRP水平明显升高,而有氧运动能明显降低ACS患者血中sICAM-1、sVCAM-1和CRP水平。

关 键 词:急性冠脉综合征    有氧运动    血清黏附分子    C反应蛋白

Effect of aerobic exercise on serum adhesion molecule and C-reactive protein in patients with acute coronary syndrome
SHI Jian-jun,JIANG Shan,LIU Yi,DONG Xiao-chao.Effect of aerobic exercise on serum adhesion molecule and C-reactive protein in patients with acute coronary syndrome[J].Chinese Heart Journal,2010,22(2):209-211.
Authors:SHI Jian-jun    JIANG Shan  LIU Yi  DONG Xiao-chao
Institution:SHI Jian-jun1,3,JIANG Shan2,LIU Yi4,DONG Xiao-chao5(1.Department of Cardiology,Medical College,Qingdao University,Qingdao 266021,Sh,ong,China,2.Department of Physiotherapy,5.Department of Cardiovascular Surgery,Xijing Hospital,4.Department of Pathophysiology,Fourth Military Medical University,Xi\'an 710032,Shaanxi,3.Second Department for Cadres,PLA 401 Hospital,Qingdao 266071,China)
Abstract:AIM: To study the effect of aerobic exercise on serum soluble intercellular adhesion molecule-1(sICAM-1),soluble vascular cellular adhesion molecule-1(sVCAM-1) and C-reactive protein(CRP) in patients with acute coronary syndrome(ACS).METHODS: Seventy patients with ACS were divided into two groups: regular treatment group and regular treatment plus aerobic exercise group.Healthy subjects were chosen as the control group.Levels of sICAM-1 and sVCAM-1 were tested by ELISA and the level of CRP was tested by imm...
Keywords:acute coronary syndrome  aerobic exercise  serum adhesion molecule  C-reactive protein  
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