Mixed growth hormone cell- prolactin cell pituitary adenoma with acromegaly: α-subunit most growth hormone cells |
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| Authors: | Shigeru Furuhata Toru Kameya Tomoko Tsuruta Heiji Naritaka Mitsuhiro Otani Shigeo Toya |
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| Affiliation: | 1. Department of Pathology, Kitasato University School of Medicine, Kanagawa
2. Department of Neurosurgery, Keio University School of Medicine, Shinanomachi, Shinjyuku-ku, 160, Tokyo, Japan
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| Abstract: | A 51 -year-old woman with mixed growth hormone (GH) cell-prolactin (PRL) cell pituitary adenoma is presented. She had clinical signs due to hypersecretion of GH and PRL. Resected tissue was studied immunohistochemically and morphologically. The serial sections revealed that GH and α-subunit were co-localized in most cells, while GH and PRL were localized in different cells. |
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