Venous thromboembolic disease and hematologic considerations in obesity |
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Authors: | Craft Mitchell K Reed Mary Jane |
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Affiliation: | Division of Critical Care Medicine, Geisinger Medical Center, 100 North Academy Avenue, Danville, PA 17822, USA. |
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Abstract: | Venous thromboembolic disease continues to be a major source of morbidity and mortality, with obese patients who are critically ill presenting some of the most at-risk patients. As the literature evolves, it has become clear that there is a complex relationship between obesity and thrombosis and atherogenesis. It is true that many of these conditions are reversible with weight loss; however, obesity remains on the rise. Management of obese patients must incorporate and consider these intricate changes in an attempt to improve patient outcomes. |
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Keywords: | Obesity Pulmonary embolism PAI-1 Venous thromboembolism Adipocytes |
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