| 小剂量生长抑素激动剂SMS201—995对正常成人胆囊收缩... |
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| 引用本文： | Alan,GH 朱显峰. 小剂量生长抑素激动剂SMS201—995对正常成人胆囊收缩...[J]. 中国医学科学院学报, 1992, 14(3): 201-205 |
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| 作者姓名： | Alan GH 朱显峰 |
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| 摘 要： |
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| 关 键 词： | 生长抑素 胆囊收缩功能 超声检查 |
Acute effect of small dosages of somatostatin analogue SMS201-995 on gallbladder contractility in normal adults] |
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| X Zhu. Acute effect of small dosages of somatostatin analogue SMS201-995 on gallbladder contractility in normal adults][J]. Acta Academiae Medicinae Sinicae, 1992, 14(3): 201-205 |
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| Authors: | X Zhu |
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| Affiliation: | PUMC Hospital, Beijing. |
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| Abstract: | Recently, a long-acting, somatostatin analogue, SMS201-995(SMS), has been developed and extensively investigated. It has been proved to be remarkably effective in treating many diseases, including active acromegaly. We observed the effect of SMS on gallbladder contractility in normal adults using the fatty meal test. Our results show that gallbladder contractility was inhibited significantly for 6 hours after the subcutaneous injection of SMS in dosages of 50, 25, 12.5, and 5 micrograms. We conclude that it is not practical to avoid gallbladder disfunction during long-term SMS treatment by decreasing the dosages of SMS. |
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