| 干细胞与胃肠道黏膜的自我更新和损伤修复 |
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| 引用本文： | 夏健龄,王立群,黄巧冰. 干细胞与胃肠道黏膜的自我更新和损伤修复[J]. 胃肠病学, 2012, 17(6): 376-378 |
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| 作者姓名： | 夏健龄 王立群 黄巧冰 |
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| 作者单位： | 1. 南方医科大学第一临床医学院,510515
2. 南方医科大学基础医学院病理生理学教研室 |
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| 摘 要： | 干细胞是一类具有自我更新和多向分化潜能的细胞。近期研究发现干细胞在胃肠道黏膜自我更新和损伤修复中发挥重要作用,其可使胃肠道黏膜处于动态平衡状态,并维持胃肠道黏膜的完整性。目前干细胞作用于胃肠道黏膜的功能和机制尚未完全明了。随着对干细胞研究的不断深入,干细胞应用将为胃肠疾病提供新的治疗手段。本文就干细胞在胃肠道黏膜自我更新和损伤修复中的作用和机制作一综述。
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| 关 键 词： | 干细胞 胃黏膜 肠黏膜 自我更新 损伤修复 |
Stem Cells and Self-renewal and Damage Repair of Gastrointestinal Mucosa |
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| XIA Jianling , WANG Liqun , HUANG Qiaobing. Stem Cells and Self-renewal and Damage Repair of Gastrointestinal Mucosa[J]. Chinese Journal of Gastroenterology, 2012, 17(6): 376-378 |
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| Authors: | XIA Jianling WANG Liqun HUANG Qiaobing |
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| Affiliation: | 1 Eight-year Clinical Medicine Program in First Clinical Medical School,Southern Medical University, Guangzhou(510515);2 Department of Pathophysiology,School of Basic Medical Sciences,Southern Medical University,Guangzhou |
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| Abstract: | Stem cells are a group of cells with the ability of undergoing self-renewal and multi-potential differentiation. Recent studies have shown that stem cells play important roles in self-renewal and damage repair of gastrointestinal mucosa, which keeps gastrointestinal mucosa in a state of dynamic balance and maintaining of its integrity.The mechanism of how the stem cells acting on gastrointestinal mucosa remains unclear yet.However,with the progress of study on stem cells,it will become a new approach for therapy of gastrointestinal diseases.This article reviewed the effect and mechanism of stem cells in self-renewal and damage repair of gastrointestinal mucosa. |
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| Keywords: | Stem Cells Gastric Mucosa Intestinal Mucosa Self-Renewal Damage Repair |
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