| 补阳还五汤预处理对缺血再灌注损伤沙鼠脑组织血流量的影响 |
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| 引用本文： | 吴晓光,李强,郭园园,陈文燕,任艳玲.补阳还五汤预处理对缺血再灌注损伤沙鼠脑组织血流量的影响[J].承德医学院学报,2011,28(2):115-117. |
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| 作者姓名： | 吴晓光 李强 郭园园 陈文燕 任艳玲 |
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| 作者单位： | 吴晓光,郭园园,陈文燕(承德医学院,河北承德,067000);李强(宽城县医院);任艳玲(承德医学院附属医院) |
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| 摘 要： | 目的:探讨补阳还五汤对缺血再灌注损伤沙鼠脑微循环血流量的影响.方法:48只长爪沙鼠随机分为4组:假手术组、模型组、补阳还五汤组和尼莫地平组.Kirino法制作沙鼠前脑缺血模型;应用激光多普勒血流仪观察脑组织血流量变化,伊文思蓝法观察血脑屏障通透性,干湿法观察脑组织含水量.结果:补阳还五汤能增加缺血1min、5min海马...
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| 关 键 词： | 补阳还五汤 缺血再灌注 血流量 |
EFFECTS OF BUYANGHUANWU DECOCTION PRETREATMENT ON MICROCIRCULATION BLOOD FLOW OF CEREBRAL ISCHEMIA AND REPERFUSION IN GERBILS |
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| WU Xiao-guang,LI Qiang,GUO Yuan-yuan,et al.EFFECTS OF BUYANGHUANWU DECOCTION PRETREATMENT ON MICROCIRCULATION BLOOD FLOW OF CEREBRAL ISCHEMIA AND REPERFUSION IN GERBILS[J].Journal of Chengde Medical College,2011,28(2):115-117. |
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| Authors: | WU Xiao-guang LI Qiang GUO Yuan-yuan |
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| Institution: | WU Xiao-guang,LI Qiang,GUO Yuan-yuan,et al(Chengde Medical College,Hebei Chengde 067000,China) |
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| Abstract: | Objective:To explore the protective mechanism of BuYangHuanWu Decoction(BHD) on microcirculation blood flow in gerbils with cerebral ischemia-reperfusion.Methods:48 male gerbils were randomly divided into 4 groups(n=12):model group,sham operation group,BHD group and Nimodipine group.Transient forebrain ischemia animal model was established by using Kirino method.The microcirculation blood flow was detected with laser-Doppler;The permeability of BBB(blood brain barrier) was assessed using evan's blue(EB) met... |
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| Keywords: | BuYangHuanWu Decoction Ischemia-reperfusion Blood flow |
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