前瞻性干预对骨科Ⅰ类切口围手术期预防使用抗菌药物合理性的影响

目的探讨前瞻性干预措施对骨科Ⅰ类切口手术围手术期抗菌药物应用合理性的影响。方法抽取骨科2013年2季度(干预前组)和2013年3季度(干预后组)Ⅰ类切口手术病例,通过典型病例分析评价围手术期抗菌药预防使用的合理性。结果同干预前比较,各项用药合理率显著提高,其中抗菌药物使用率显著下降(从89.2%降到了47.7%),抗菌药物应用合理率显著上升(从51.2%上升到了93.5%)。结论临床药师通过前瞻性用药干预降低了Ⅰ类切口围手术期抗菌药物的使用率,并提高了围手术期抗菌药预防应用的合理率,为提高围手术期抗菌药物的合理应用提供了实践支持。

THE EFFECT OF PROSPECTIVE INTERVENTION ON THE APPLICATION OF ANTIBIOTICS DURING PERI -OPERATION PERIOD OF TYPE I INCISION IN DEPARTMENT OF ORTHO- PEDICS

Objective To investigate the effect of prospective intervention on the application of antibiotics during peri - operation period of type I incision in department of orthopedics. Methods We randomly extracted type I incision operation case in the second quarter （the pre- intervention group） and the third quarter （the intervention group） of orthopedics department in 2013, and further evaluated rationality of antibacterial prophylaxis during peri - operation period through the typical case. Results Compared with pre - intervention group, reasonable medication indexes were significantly improved, such as antibiotics using rate significantly decreased （from 89. 2% to 47.7% ） ; Reasonable antibiotics application rate increased significantly （from 51.2% to 93.5% ）. Conclusion Prospective intervention could effectively reduce the use of antimicrobial drugs and improve the rational application rate of antibi- otics peri - operation during peri - operation period of type I incision in department of orthopedics, which provids practical basis for improving rational application of antimicrobial agents in peri - operative operation.