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Assessment of Diffuse Thyroid Disease by Strain Ratio in Ultrasound Elastography
Affiliation:1. Department of Ultrasonography, Binzhou Medical University Hospital, Binzhou, Shandong Province, China;2. Department of Ultrasound, Huashan Hospital, Fudan University, Shanghai, China;3. Department of Radiology, The People''s Hospital of Binzhou, Binzhou, Shangdong Province, China;1. Department of Radiology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri-si, Gyeonggi-do, Korea;2. Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Gangnam-gu, Seoul, Korea;3. Department of Radiology, Ajou University Hospital, Ajou University College of Medicine, Yeongtong-gu, Suwon, Korea;4. Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri-si, Gyeonggi-do, Korea;1. Department of Neuroscience, Karolinska Institutet, Sweden;2. Neuropediatric Unit, Dept of Women''s and Children''s Health, Karolinska Institutet, Sweden
Abstract:The goal of this study was to explore the value of strain ratio from real-time elastography in the semi-quantitative assessment of diffuse thyroid disease. Fifty-one patients with primary hyperthyroidism, 70 with Hashimoto's thyroiditis, 8 with subacute thyroiditis and 43 with normal healthy thyroids were recruited to measure the strain ratio (SR) of thyroid tissue and sternocleidomastoid muscle (on the same side of the thyroid). SR values of all groups were subjected to statistical analysis. The SRs (mean ± standard deviation) of patients with hyperthyroidism, Hashimoto's thyroiditis and subacute thyroiditis were 2.30 ± 1.08, 7.04 ± 7.74 and 24.09 ± 13.56, respectively. The SR of the control group was 1.76 ± 0.54. SR values ranked in ascending order were control group < hyperthyroidism group < Hashimoto's thyroiditis group < subacute thyroiditis group. There were statistically significant (p < 0.05) differences in thyroid hardness between groups with different diffuse thyroid diseases. SR values of the hyperthyroidism and control groups did not statistically differ (p > 0.05). It is feasible to assess diffuse thyroid disease with strain ratios obtained with ultrasound elastography.
Keywords:Diffuse thyroid disease  Real-time elastography  Strain ratio  Ultrasound
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