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Diphtheria,tetanus and poliovirus antibody persistence 5 years after vaccination of pre-schoolers with two different diphtheria,tetanus and inactivated poliomyelitis vaccines (Td-IPV or DT-IPV) and immune responses to a booster dose of DTaP-IPV
Institution:1. Paediatric Department, Hôpital Antoine Béclère, Hôpitaux Universitaires Paris-Sud, 157 Rue de la Porte de Trivaux, 92140 Clamart, France;2. Université Paris Sud, Le Kremlin Bicêtre, Orsay France;3. Sanofi Pasteur SA, 2 avenue Pont Pasteur, 69367 Lyon Cedex 07, France;4. Sanofi Pasteur MSD, 162 avenue Jean Jaurès, CS 50712, 69367 Lyon Cedex 07, France;1. Medical University Clinic, Cantonal Hospital Baselland, Liestal and University of Basel, Basel, Switzerland;2. Department of Clinical Pharmacology and Toxicology, University Hospital Basel and University of Basel, Basel, Switzerland;3. Department of Hematology, University Hospital Basel and University of Basel, Basel, Switzerland;1. Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA, United States;2. Division of Infectious Diseases, Department of Medicine, Brigham and Women''s Hospital, Boston, MA, United States;3. US Food and Drug Administration Center for Biologics Evaluation and Research, Rockville, MD, United States;4. Division of Infectious Diseases, Department of Medicine, Boston Children''s Hospital, Boston, MA, United States;1. GSK, Avenue Fleming 20, 1300 Wavre, Belgium;2. Deloitte Belgium, Luchthaven Nationaal 1 J, 1930 Zaventem, Belgium;3. Department of Health Economics and Health Care Management, School of Public Health, Bielefeld University, Universitätsstraße 25, 33615 Bielefeld, Germany;4. Université Paris Descartes, Sorbonne Paris Cité, Inserm CIC 1417, Assistance Publique Hopitaux de Paris (APHP), CIC Cochin-Pasteur, rue du Faubourg St Jacques 27, 75679 Paris cedex 14, France;5. GSK, Great West Road 980, Brentford TW8 9GS, UK;6. Institute of Public Health, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy;7. Unit of PharmacoTherapy, -Epidemiology & -Economics, University of Groningen, Groningen Research Institute of Pharmacy, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands;8. Department of Health Sciences, University of Groningen, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands;9. Department of Economics, Econometrics & Finance, University of Groningen, Faculty of Economics & Business, Groningen, The Netherlands;10. European Center of Pharmaceutical Medicine, University of Basel, Klingelbergstrasse 61, 4056 Basel, Switzerland;1. Paediatrics, Flinders University and Flinders Medical Centre, Bedford Park, Adelaide 5042, Australia;2. Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA;3. Medizin Krefeld MVZ, Krefeld 47805, Germany;4. University of Basel Children’s Hospital, Basel 4056, Switzerland;5. Max Super Speciality Hospital, Shalimar Bagh, New Delhi 110088, India;6. Department of Pediatrics, University of Pennsylvania and Vaxconsult, Doylestown, PA 19104, USA
Abstract:
Keywords:Vaccines  Booster response  Td-IPV  DT-IPV  DTaP-IPV  Antibody persistence  Safety  ANSM"}  {"#name":"keyword"  "$":{"id":"kw0045"}  "$$":[{"#name":"text"  "_":"Agence Nationale de Sécurité du Médicament et des Produits de Santé (the French national agency for the safety of drugs and health products)  aP"}  {"#name":"keyword"  "$":{"id":"kw0055"}  "$$":[{"#name":"text"  "_":"standard dose of acellular pertussis vaccine  ap"}  {"#name":"keyword"  "$":{"id":"kw0065"}  "$$":[{"#name":"text"  "_":"low dose of acellular pertussis vaccine  BS"}  {"#name":"keyword"  "$":{"id":"kw0075"}  "$$":[{"#name":"text"  "_":"blood sample  CI"}  {"#name":"keyword"  "$":{"id":"kw0085"}  "$$":[{"#name":"text"  "_":"confidence interval  DTaP-IPV"}  {"#name":"keyword"  "$":{"id":"kw0095"}  "$$":[{"#name":"text"  "_":"diphtheria  tetanus  aP and IPV types 1–3 vaccine  DT-IPV"}  {"#name":"keyword"  "$":{"id":"kw0105"}  "$$":[{"#name":"text"  "_":"combined booster of standard-dose diphtheria  tetanus and IPV types 1–3 vaccine  ELISA"}  {"#name":"keyword"  "$":{"id":"kw0115"}  "$$":[{"#name":"text"  "_":"enzyme-linked immunosorbent assay  EU"}  {"#name":"keyword"  "$":{"id":"kw0125"}  "$$":[{"#name":"text"  "_":"European Union  GMC"}  {"#name":"keyword"  "$":{"id":"kw0135"}  "$$":[{"#name":"text"  "_":"geometric mean concentration  GMCR"}  {"#name":"keyword"  "$":{"id":"kw0145"}  "$$":[{"#name":"text"  "_":"geometric mean of individual post-/pre-booster antibody concentrations ratio  GMT"}  {"#name":"keyword"  "$":{"id":"kw0155"}  "$$":[{"#name":"text"  "_":"geometric mean titre  GMTR"}  {"#name":"keyword"  "$":{"id":"kw0165"}  "$$":[{"#name":"text"  "_":"geometric mean of individual post-/pre-booster antibody titres ratio  IPV"}  {"#name":"keyword"  "$":{"id":"kw0175"}  "$$":[{"#name":"text"  "_":"inactivated poliovirus vaccine  SPC"}  {"#name":"keyword"  "$":{"id":"kw0185"}  "$$":[{"#name":"text"  "_":"Summary of Product Characteristics  SN"}  {"#name":"keyword"  "$":{"id":"kw0195"}  "$$":[{"#name":"text"  "_":"seroneutralization  Td-IPV"}  {"#name":"keyword"  "$":{"id":"kw0205"}  "$$":[{"#name":"text"  "_":"combined booster of low-dose diphtheria  tetanus and IPV types 1–3 vaccine  WHO"}  {"#name":"keyword"  "$":{"id":"kw0215"}  "$$":[{"#name":"text"  "_":"World Health Organization
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