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Estimating the cost of cholera-vaccine delivery from the societal point of view: A case of introduction of cholera vaccine in Bangladesh
Affiliation:1. International Centre for Diarrheal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh;2. Institute of Epidemiology, Disease Control and Research (IEDCR), DGHS, Dhaka, Bangladesh;3. Liverpool School of Tropical Medicine, Pembroke Place, United Kingdom;4. Karolinska Institutet, Stockholm, Sweden;1. IDF Medical Corps, Israel;2. Department of Military Medicine, Hebrew University Faculty of Medicine, Jerusalem, Israel;3. University of Rochester Medical Center, Rochester, NY, USA;4. Hebrew University – Hadassah Braun School of Public Health and Community Medicine, Jerusalem, Israel;1. Health Economics Research Unit, Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, Scotland, UK;2. Management and Economics Research Center, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran;3. Gastrointestinal and Liver Disease Research Center (GILDRC), Iran University of Medical Sciences, Tehran, Iran;4. Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA;5. Department of Community Medicine, Iran University of Medical Sciences, Tehran, Iran;6. Department of Pediatrics, Iran University of Medical Sciences, Tehran, Iran;7. Pediatric Infections Research Center, Mofid Children''s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran;8. Center for Communicable Disease Control, Ministry of Health and Medical Education, Tehran, Iran;9. Tehran University of Medical Sciences, Tehran, Iran;10. Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK;11. School of Medical Education, Shahid Beheshti University of Medical Sciences, Tehran, Iran;12. Regional Office for the Eastern Mediterranean, World Health Organization, Cairo, Egypt;13. PATH, Seattle, WA, USA;14. Agence de Médecine Préventive, Paris, France;15. Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran;p. Center for Nursing Care Research, Iran University of Medical Sciences, Tehran, Iran
Abstract:Cholera is a major global public health problem that causes both epidemic and endemic disease. The World Health Organization recommends oral cholera vaccines as a public health tool in addition to traditional prevention practices and treatments in both epidemic and endemic settings. In many developing countries like Bangladesh, the major issue concerns the affordability of this vaccine. In February 2011, a feasibility study entitled, “Introduction of Cholera Vaccine in Bangladesh (ICVB)”, was conducted for a vaccination campaign using inactivated whole-cell cholera vaccine (Shanchol) in a high risk area of Mirpur, Dhaka. Empirical data obtained from this trial was used to determine the vaccination cost for a fully immunized person from the societal perspective. A total of 123,661 people were fully vaccinated receiving two doses of the vaccine, while 18,178 people received one dose of the same vaccine. The total cost for vaccine delivery was US$ 492,238 giving a total vaccination cost per fully-vaccinated individual of US$ 3.98. The purchase cost of the vaccine accounted for 58% of the overall cost of vaccination. Attempts to reduce the per-dose cost of the vaccine are likely to have a large impact on the cost of similar vaccination campaigns in the future.
Keywords:Cholera  Vaccine  Cost  Health economics  Bangladesh
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