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Influenza and pertussis vaccination coverage in pregnant women
Institution:1. KU Leuven, University of Leuven, Department of Pharmaceutical and Pharmacological Sciences, Leuven University Vaccinology Center (LUVAC), B-3000 Leuven, Belgium;2. KU Leuven, University of Leuven, Department of Public Health and Primary Care, Centre for Environment and Health, Youth Health Care, B-3000 Leuven, Belgium;3. KU Leuven, University of Leuven, Department of Development and Regeneration, Department of Obstetrics and Gynaecology, University Hospitals Leuven, B-3000 Leuven, Belgium;1. Centre for the Evaluation of Vaccination, Vaccine & Infectious Disease Institute, University of Antwerp, Antwerp, Belgium;2. Agency for Care and Health, Infectious Disease Control and Vaccination, Brussels, Belgium;1. Kaiser Permanente Vaccine Study Center, 1 Kaiser Plaza, 16B, Oakland, CA 94612, USA;2. National Vaccine Program Office, Office of the Assistant Secretary for Health, US Department of Health and Human Services, USA;1. Department of Obstetrics and Gynecology, Monash University, Melbourne, Australia;2. Ritchie Center, Hudson Institute of Medical Research, Melbourne, Australia;3. Monash Health, Melbourne, Australia;1. School of Nursing, Li Ka Shing Faculty of Medicine, 21 Sassoon Road, Pokfulam, Hong Kong;2. Queen Mary Hospital, 102 Pokfulam Road, Pokfulam, Hong Kong;3. Department of Obstetrics and Gynaecology, Kwong Wah Hospital, 25 Waterloo Road, Kowloon, Hong Kong;4. Department of Obstetrics and Gynaecology, Tuen Mun Hospital, 23 Tsing Chung Koon Road, Tuen Mun, New Territories, Hong Kong;1. Vaccine Evaluation Center, BC Children''s Hospital, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada;2. Vanderbilt Vaccine Research Program, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA;3. Canadian Center for Vaccinology, Departments of Pediatrics and Microbiology and Immunology, Dalhousie University, Izaak Walton Killam Health Centre, and Nova Scotia Health Authority, Halifax, NS, Canada
Abstract:BackgroundPregnant women have an increased risk for complications and hospitalizations when infected with the influenza virus in the second or third trimester. Additionally, infants under six months of age are most vulnerable when contracting pertussis. Immunization against influenza and pertussis during pregnancy provides protection for mother and neonate against influenza and for neonates against pertussis pending protection through infant immunization. In Belgium, a gradual increase in pertussis cases over the past decade was observed. This study was undertaken to document vaccination coverage for influenza and pertussis and factors related to vaccination status in pregnant women.MethodsTwo hundred and fifty pregnant women completed a questionnaire during their third trimester. Vaccination data were collected and reasons for non-vaccination were noted as well as socio-demographic data which are known to influence vaccination coverage.ResultsA documented vaccination coverage of 42.8% for influenza and 39.2% for pertussis was observed. Taking into account doses which were not documented, but administered according to the expectant mother, coverage for influenza would increase to 62% and for pertussis to 46%. The most important reasons for non-vaccination were the absence of a recommendation by medical staff (9.6%) and delay in vaccination (8.4%). The GP was the most important vaccinator. Pregnant women with a lower education and those with a foreign origin were more vulnerable for non-vaccination.ConclusionIncomplete documentation is the most important barrier in determining the vaccination status of pregnant women. Immunization during pregnancy needs further integration through vaccination campaigns aimed at both health care providers and pregnant women.
Keywords:Influenza  Pertussis  Pregnancy  Vaccination coverage  Immunization  GP"}  {"#name":"keyword"  "$":{"id":"kw0035"}  "$$":[{"#name":"text"  "_":"general practitioner  HCP"}  {"#name":"keyword"  "$":{"id":"kw0045"}  "$$":[{"#name":"text"  "_":"health care provider
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