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Socioeconomic status and HIV vaccine preparedness studies in North America
Affiliation:1. Department of Infectious Disease, the Second Affiliated Hospital of the Southeast University, Nanjing 210003, China;2. Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA;3. Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA;4. Beijing You’an Hospital, Capital Medical University, No. 8 Xitoutiao, You’an men wai, Fengtai District, Beijing 100069, China;5. Division of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA;1. School of Architecture and Urban Planning, Chongqing University, 174 Shazheng Ave., Shapingba District, Chongqing 400044, China;2. Urban Big Data Centre, University of Glasgow, 7 Lilybank Gardens, Glasgow G12 8RZ, UK;3. Edward J. Bloustein School of Planning and Public Policy, Rutgers University, 33 Livingston Ave., New Brunswick, NJ 08901, USA;1. Graduate School of Economics, Kyoto University, Yoshida-honmachi, Sakyo-ku, Kyoto, 606-8501, Japan;2. School of Economics, Capital University of Economics and Business, Zhangjialukou-121, Fengtai District, Beijing, 10070, China;1. Bank of Finland Institute for Economies in Transition (BOFIT), Helsinki, Finland;2. Max Planck Institute for Research on Collective Goods, Bonn, Germany;3. EM Strasbourg Business School, University of Strasbourg, France
Abstract:Educational level, employment, and income are key components of socioeconomic status (SES). This article is a systematic review of SES variables in North American countries, and their relationship to willingness to participate (WTP) and retention in a hypothetical preventive phase 3 HIV vaccine trial and in actual HIV vaccine trials. Men who have sex with men (MSM) tended to have higher educational levels, be more employed, and had higher income levels than injection drug users (IDU) and women at heterosexual risk (WAHR). In large part, there was no relationship between educational level and WTP, as well as between educational level and retention. Similarly, there was no relationship between employment and WTP. In WAHR who were African-American, those employed were less likely than others to complete the study at 18 months. The exact occupations of participants analyzed have not been specified, and specification of these occupations may help determine whether enhanced retention (ER) strategies are required.
Keywords:HIV vaccine  Socioeconomic status  Willingness to participate  Retention
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