| 利用X-刀治疗重症肌无力的临床疗效分析 |
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| 引用本文： | 徐金枝,潘邓记,陆长峰,张润希,杨明山,陈源. 利用X-刀治疗重症肌无力的临床疗效分析[J]. 华中科技大学学报(医学版), 2002, 31(4): 440-441,445 |
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| 作者姓名： | 徐金枝 潘邓记 陆长峰 张润希 杨明山 陈源 |
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| 作者单位： | 1. 华中科技大学同济医学院附属同济医院神经科,武汉,430030
2. 华中科技大学同济医学院附属同济医院肿瘤科,武汉,430030 |
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| 摘 要： | 对8例重症肌无力（myasthenia gravis,MG)伴胸腺瘤患者行X-刀治疗，结果显示稳定缓解5例，药物缓解2例，部分缓解1例，未见明显的肌无力加重或诱发危象及其它不良反应，其中5例术后6个月复查纵隔CT或MRI发现胸腺瘤体积较治疗前缩小，1例无明显变化，8例患者治疗前后的AchRab和CAEab滴度均有下降，提示：该方法疗效可靠，具有微侵袭。高精度，准确安全的特点，对病情危重，年龄大，不宜手术治疗的合并胸腺异常的MG患者是一种安全有效的治疗方法。
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| 关 键 词： | 重症肌无力 胸腺瘤 X－刀 治疗 |
X-knife Therapy for Myasthenia Gravis |
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| Xu Jinzhi,Pan Dengji,Lu Changfeng et al. X-knife Therapy for Myasthenia Gravis[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 2002, 31(4): 440-441,445 |
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| Authors: | Xu Jinzhi Pan Dengji Lu Changfeng et al |
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| Affiliation: | Xu Jinzhi,Pan Dengji,Lu Changfeng et al Department of Neurology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030 |
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| Abstract: | Eight cases of myasthenia gavis (MG) associated with thymoma were subjected to X knife therapy. The results showed that 5 cases stably relieved, 2 relieved with drug therapy and one partially relieved. No obvious myasthenia aggravation, myasthenic crisis induction or other side effects were found. Six months later, CT or MRI reported the tumor size of 5 cases out of 8 cases was reduced as compared with before x knife treatment, and one case had no obvious change. The concentrations of AchRab and CAEab of all the 8 cases were decreased. It was suggested that the x knife therapy for MG had reliable effectiveness with microinvasion, high accuracy and safety, especially suitable to MG patients whose disease condition was serious and age was older and those who couldn't be subjected to operation. |
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| Keywords: | myasthenia gravis thymoma X knife therapy |
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