中国多中心药物洗脱支架急性或亚急性血栓的调查

目的调查国内药物洗脱支架的急性或亚急性血栓发生率,与金属裸支架相比,评价其安全性。方法收集国内84个心脏介入中心近两年的经皮冠状动脉介入治疗资料和血栓病例,并汇总分析。结果支架术总例数为31412例,其中药物洗脱支架置入术占32.7%,金属裸支架置入术占67.3%。二者的血栓发生率分别为0.77%和0.75%。结论药物洗脱支架的安全性与金属裸支架相似。

China multi-center study of acute and sub-acute thrombosis incidence following implantation of drug-eluting stent

Objective This study was designed to investigate the incidence of acute or sub-acute thrombosis following implantation of drug-eluting stents (DES) and to compare it with bare metal stents to evaluate the DES safety. Methods Clinical data of PCI and thrombosis cases was collected for 2003 and 2004 in 84 interventional heart centers nationwide and all the data underwent statistical analysis. Results Totally 31?412 stenting cases were analyzed in the study, of which stenting with DES and with BMS were 32.7% and 67.3% respectively. The incidence of thrombosis with DES and with BMS were 0.77% and 0.75% respectively. Conclusion In tems of thrombosis, Drug-eluting stent is as safe as bare metal stent.