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An approach to the toxicity and toxicokinetics of aflatoxin B1 and ochratoxin A after simultaneous oral administration to fasted F344 rats
Authors:L.A. Corcuera,A. Vettorazzi,L. Arbillaga,E. Gonzá  lez-Peñ  as,A. Ló  pez de Cerain
Affiliation:1. Department of Nutrition, Food Sciences, Physiology and Toxicology, Faculty of Pharmacy (C.I.F.A), University of Navarra, Irunlarrea 1, E-31008 Pamplona, Spain;2. Department of Organic and Pharmaceutical Chemistry, Faculty of Pharmacy (C.I.F.A), University of Navarra, Irunlarrea 1, E-31008 Pamplona, Spain
Abstract:Humans are exposed to the hepatotoxic aflatoxin B1 (AFB1) and nephrotoxic ochratoxin A (OTA) through diet. However, kinetic and toxicological data after their co-administration are scarce.
Keywords:Aflatoxin B1   Ochratoxin A   Toxicity   Toxicokinetic   Simultaneous administration
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