Exposición a radón residencial y cáncer de pulmón en nunca fumadores. Resultados preliminares del estudio LCRINS |
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Authors: | Alberto Ruano-Ravina,Luciana Prini-Guadalupe,Juan Miguel Barros-Dios,José Abal-Arca,Virginia Leiro-Ferná ndez,Ana Isabel Gonzá lez-Silva,Antonio Golpe-Gó mez,Francisco Javier Gonzá lez-Barcala,Carolina Pena,Carmen Montero-Martí nez,Cristina Martí nez-Gonzá lez,Marí a José Mejuto-Martí ,Alejandro Veres-Racamonde |
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Affiliation: | 1. Área de Medicina Preventiva y Salud Pública, Universidad de Santiago de Compostela, Santiago de Compostela, La Coruña, España;2. CIBER de Epidemiología y Salud Pública, CIBERESP, España;3. Servicio de Medicina Preventiva, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, La Coruña, España;4. Servicio de Neumología, Complejo Hospitalario Universitario de Ourense, Ourense, España;5. Servicio de Neumología, Complexo Hospitalario Universitario de Vigo (CHUVI), Vigo, Pontevedra, España;6. Servicio de Neumología, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, La Coruña, España;g Servicio de Oncología, Complejo Hospitalario de Pontevedra, Pontevedra, España;h Servicio de Neumología, Complejo Hospitalario Universitario de A Coruña, La Coruña, España;i Área del Pulmón, Instituto Nacional de Silicosis-Hospital Universitario Central de Asturias (INS-HUCA), Oviedo, España;j Servicio de Neumología, Hospital Arquitecto Marcide, Ferrol, La Coruña, España;k Servicio de Neumología, Hospital Universitario Lucus Augusti, Lugo, España |
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Abstract: | Introduction and objectiveResidential radon is the second most important risk factor for lung cancer and the first among never-smokers. The objective of this study is to report the concentrations of residential radon in a series of never-smoker cases recruited in a multicenter study of cases and controls in northwestern Spain. In this study, all the hospitals in the Spanish province of Galicia and one from Asturias participated.Patients and methodsThe present article includes a series of cases with residential radon measurements. All the subjects were personally interviewed, 3 ml of blood were taken from each, and they were each given instructions about how to place a residential radon detector in their homes.ResultsSixty-nine case subjects were recruited, 84% of whom were women with a mean age of 71, and 81% of whom had adenocarcinoma. The average concentration of residential radon in the cases was 237 Bq/m3, while the average concentration in the Galician population is 79 Bq/m3. No relationship was observed between the concentration of residential radon and either sex or age at the time of diagnosis of the cases, but there was a tendency towards having a greater concentration in those diagnosed with small-cell and large-cell carcinoma.ConclusionsThe concentrations of residential radon in the cases included are very high at about three times the average concentration of residential radon to which the general population of Galicia is exposed. |
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Keywords: | Cá ncer de pulmó n Radó n residencial Españ a Estudio de casos y controles |
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