Streptococcus pneumoniae isolates from middle ear fluid and nasopharynx of children with acute otitis media exhibit phase variation |
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| Authors: | Arai Jun Hotomi Muneki Hollingshead Susan K Ueno Yumi Briles David E Yamanaka Noboru |
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| Affiliation: | 1Department of Otolaryngology—Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan;2Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama |
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| Abstract: | Pneumococcal phase variation of 37 middle ear and 31 nasopharyngeal isolates obtained from children with acute otitis media was examined in the absence of intervening culture. The fraction of the opaque colonies was significantly higher in middle ear isolates than in nasopharyngeal isolates. The difference is probably the result of the pneumococci adapting to differential selective environments. |
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