| 露蕊乌头生物碱的研究(Ⅰ) |
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| 引用本文： | 蒋山好,郭素华,周炳南,王生新,伊甫生,纪兰菊. 露蕊乌头生物碱的研究(Ⅰ)[J]. 药学学报, 1986, 21(4): 279-284 |
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| 作者姓名： | 蒋山好 郭素华 周炳南 王生新 伊甫生 纪兰菊 |
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| 作者单位： | *上海中医学院药学系80届,毕业实习学生;中国科学院上海药物研究所;中国科学院西北高原生物研究 |
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| 摘 要： | 从藏药露蕊乌头(Aconitum gymnandrum Maxim)中分得四个生物碱,经化学和光谱鉴定,其中两个为已知生物碱atisine.Hcl(A)和talatisamine(B),另两个为新的二萜类生物碱,分别命名为露乌碱,(C)(gymnaconitine)和甲基露乌碱(D)(mgthyl gymnaconitine),这两种新的生物碱均联接有二甲基咖啡酸酯:在乌头生物碱中是首次发现。
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| 关 键 词： | 藏药 露蕊乌头 生物碱 atisine.Hcl talatisamine露乌碱 甲基露乌碱 二甲基咖啡酸酯 |
| 收稿时间： | 1984-10-23 |
Alkaloids from Aconitum gymnandrum maxim (I) |
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| JIANG Shan-Hao,GUO Su-Hua,ZHOU Bing-Nan,WANG Sheng-Xin,YI Fu-Sheng and JI Lan-Ju. Alkaloids from Aconitum gymnandrum maxim (I)[J]. Acta pharmaceutica Sinica, 1986, 21(4): 279-284 |
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| Authors: | JIANG Shan-Hao GUO Su-Hua ZHOU Bing-Nan WANG Sheng-Xin YI Fu-Sheng JI Lan-Ju |
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| Abstract: | In addition to atisine and talatisamine, two new alkaloids, gymnaconitine (C), C34H47O8N, and methylgymnaconitine (D), C35H49O8N, have been isolated from Aconitum gymnandrum Maxim. The chemical structures of gymnacontine and methylgymnaconitine were established by UV, IR, 1H NMR, 13C NMR and MS spectral data and chemical evidence.It should be pointed out that it is found for the first time in the research of Aconitum alkaloids that both gymnaconitine and methylgymnaconitine contain 3,4-O-dimethyl-caffeic ester. |
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| Keywords: | Alkaloid Atisine Talatisamine Gymnaconitine Methyl gymnconitine 3,4-O-Dimethyl-caffeic ester Aconitum gymnandrum Maxim |
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