| 肠道菌群及其代谢产物与心血管疾病关系的研究进展 |
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| 引用本文： | 侯 灿,曹海涛. 肠道菌群及其代谢产物与心血管疾病关系的研究进展[J]. 南京医科大学学报(自然科学版), 2019, 0(1): 149-152 |
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| 作者姓名： | 侯 灿 曹海涛 |
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| 作者单位： | 南京医科大学附属常州第二人民医院心内科，江苏 常州 213000,南京医科大学附属常州第二人民医院心内科，江苏 常州 213000 |
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| 基金项目： | 江苏省卫生健康委科研课题（Z2018031） |
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| 摘 要： | 肠道菌群及其代谢产物在心血管疾病（cardiovascular disease，CVD）中具有重要作用。肠道菌群的组成变化及其代谢产物与动脉粥样硬化、心肌梗死、心衰、高血压的发生、发展相关。肠道菌群及其代谢产物对CVD影响的机制已有报道。本文将综述肠道菌群及其代谢产物在动脉粥样硬化、心肌梗死、心衰心功能不全、高血压的发生、发展中的作用和机制，以及在CVD防治方面的潜在价值，为CVD的防治提供新思路。
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| 关 键 词： | 肠道菌群；代谢产物；心血管疾病 |
| 收稿时间： | 2018-03-24 |
| 修稿时间： | 2018-11-03 |
Progress in the relationship between intestinal floras and their metabolites and cardiovascular diseases |
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| Hou Can and Cao Haitao. Progress in the relationship between intestinal floras and their metabolites and cardiovascular diseases[J]. Acta Universitatis Medicinalis Nanjing, 2019, 0(1): 149-152 |
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| Authors: | Hou Can and Cao Haitao |
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| Abstract: | The intestinal flora and its metabolites have an important role in cardiovascular disease (CVD). Changes in the composition of intestinal flora and its metabolites are related to the occurrence and development of atherosclerosis, myocardial infarction, heart failure, and hypertension. The mechanism of the effects of intestinal flora and its metabolites on CVD has been reported. This article will review the role and mechanism of intestinal flora and its metabolites in the development and progression of atherosclerosis, myocardial infarction, heart failure, and hypertension, as well as the potential value in the prevention and treatment of CVD, providing new insights into the prevention and treatment of CVD. |
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| Keywords: | Intestinal flora metabolites cardiovascular diseases |
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