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ZFminus1: A strategy to reduce animal tests for developmental toxicity testing by a combined use of mammalian models and the zebrafish embryotoxicity test (ZFET or ZETA)
Affiliation:1. UFZ – Helmholtz Centre for Environmental Research, Department Bioanalytical Ecotoxicology, Leipzig, Germany;2. Sanofi-Aventis Deutschland GmbH, R&D DSAR/Preclinical Safety FF, Frankfurt am Main, Germany;1. Preclinical development and safety, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340 Beerse, Belgium;2. Wil Research, a Charles River Company, 329 impasse du Domaine Rozier, 69210 Saint-Germain-Nuelles, France;1. Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, OH, USA;2. Center for Environmental Genetics, University of Cincinnati Medical Center, Cincinnati, OH, USA;3. Cincinnati Cancer Center, Cincinnati, OH, USA;4. Cincinnati Veteran Affairs Hospital Medical Center, Cincinnati, OH, USA;1. Division of Toxicology, Wageningen University, The Netherlands;2. National Institute of Public Health and the Environment (RIVM), Bilthoven, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands;3. BASF SE, Experimental Toxicology and Ecology, Ludwigshafen, Germany
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