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Recurrent Fat Embolic Strokes in a Patient With Duchenne Muscular Dystrophy With Long Bone Fractures and a Patent Foramen Ovale |
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| Affiliation: | 1. Division of Cardiology, Department of Internal Medicine, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan;2. Department of Family Medicine, Taipei City Hospital, Renai Branch, Taipei, Taiwan;3. Division of Nephrology, Department of Internal Medicine, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan;1. Department of Family Medicine, Medical University of Lublin, Lublin, Poland;2. Department of Clinical Physiology, Karolinska Institutet, Stockholm, Sweden;3. Nicollier-Schlegel SARL, Trélex, Switzerland;4. Department of Internal Diseases, 1st Military Hospital, Lublin, Poland;5. Department of Internal Diseases, Medical University of Lublin, Lublin, Poland;6. Faculty of Medicine and Health Science, The Jan Kochanowski University, Kielce, Poland;1. Department of Physics, Indian Institute of Technology, Kharagpur 721302, India;2. Department of Physics, Indian Institute of Technology, Patna 800013, India |
| Abstract: | BackgroundIndividuals with Duchenne muscular dystrophy have an increased risk of long bone fractures. Such fractures are sometimes associated with brain dysfunction due to fat embolism syndrome, although this syndrome has seldom been documented in muscular dystrophy patients.Patient DescriptionWe describe a child with Duchenne muscular dystrophy who developed fat embolism syndrome with neurological dysfunction following multiple long bone fractures. He experienced recurrent cerebral infarctions that probably resulted from embolization through a patent foramen ovale. The patent foramen ovale was closed by an occluder device in the cardiac catheterization laboratory, and he did not experience further infarctions.ConclusionsFat embolism with ischemic cerebral infarction can occur in individuals with Duchenne muscular dystrophy following long bone fractures. In this setting it is important to identify and close atrial level shunts in order to prevent additional infarctions. |
| Keywords: | Duchenne muscular dystrophy fat embolism syndrome atrial septal defect patent foramen ovale cardiomyopathy stroke |
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