慢性化脓性中耳炎分泌物的细菌培养及药敏试验

目的 :了解慢性化脓性中耳炎 (CSOM )患耳脓性分泌物的细菌分布及药物敏感性 ,以指导临床用药。方法 :采集 92例武汉地区CSOM患者手术中的中耳炎性分泌物 ,分别进行需氧菌、厌氧菌培养及药物敏感试验。结果 :需氧菌培养阳性者 75例 ,阳性率 81.5 % ,主要致病菌为绿脓杆菌、金黄色葡萄球菌和变形杆菌。 3种致病菌均对环丙沙星敏感 (敏感率为 89.0 %、88.2 %和 85 .0 % )。厌氧菌培养阳性者 10例 ,阳性率 10 .9%。结论 :绿脓杆菌、金黄色葡萄球菌和变形杆菌是武汉地区CSOM的主要致病菌 ,三者对环丙沙星类抗生素的敏感率均较高。厌氧菌在CSOM的发病中起着重要的作用。

The clinical investigation of bacteriology of chronic suppurative otitis media

Objective:To understand bacteriology of chronic suppurative otitis media (CSOM) and drug sensitivity of isolated bacteria for better treatment of CSOM. Method:Secretions of 92 samples with chronic suppurative otitis media were collected and cultured for aerobic and anaerobic bacteria respectively. Drug sensitivity test of isolated bacteria was done. Result: Aerobic bacteria was found in 75 of 92 samples ( 81.5 %), the main pathogens were pseudomonas aeruginosa?aureus staphylococcus and bacillus proteus, and their sensitive rates for ciprofloxacin were 89.0 %? 88.2 % and 85.0 % respectively. Anaerobic bacteria was found in 10 samples( 10.9 %) and the relative sensitive drug was cefoperazone sodium. Conclusion: Pseudomonas aeruginosa?aureus staphylococcus and bacillus proteus are the main pathogens of chronic suppurative otitis media, and their sensitive rates for ciprofloxacin are high.