甲状腺功能亢进症合并脑静脉窦血栓1例并文献复习

目的探讨甲状腺功能亢进症(简称甲亢)合并脑静脉窦血栓的发病机制及临床特点。方法报道1例我院诊治的甲亢合并脑静脉窦血栓的临床资料,结合文献对甲亢合并脑静脉窦血栓的临床表现及发病机制予以分析总结。结果甲亢合并脑静脉窦血栓以青年女性多见,常与甲亢的发生及其控制不佳有关;甲亢患者血液高凝状态及甲状腺肿压迫引起血流动力学异常与脑静脉窦血栓形成有关。甲亢合并脑静脉窦血栓患者中有77.42%表现为重症静脉窦血栓,其治愈率为87.1%,死亡率为3.2%。结论甲亢是脑静脉窦血栓形成的少见病因,其临床症状重,积极治疗后大多数预后较好。

Hyperthyroidism associated with cerebral venous sinus thrombosis:one case report and literature review

Objective To investigate the pathogenesis and clinical features of cerebral venous sinus thrombosis ( CVST) in patients with hyperthyroidism .Methods Report a case of hyperthyroidism with CVST in the Neurology Depart-ment and to summarize manifestations and pathogenesis of the relevant literature .Results Hyperthyroidism associated with CVST is common in young women ,which is related to the occurrence and the poor control of hyperthyroidism .The formation of CVST is associated with hypercoagulability of patients with hyperthyroidism and the abnormal hemodynamics cased by goiter's presser.77.42% of the patients present as severe CVST ,witch crue rate is 87.1% and mortality is 3.2%. Conclusion Hyperthyroidism is a rare pathogeny of CVST .Despite its clinical symptoms severely ,the prognosis is favora-ble for most patients after positive treatment .