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Randomized trial of systemic hypothermia selectively protects the cortex on MRI in term hypoxic-ischemic encephalopathy |
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| Authors: | Inder Terrie E Hunt Rod W Morley Colin J Coleman Lee Stewart Michael Doyle Lex W Jacobs Susan E |
| Institution: | Division of Newborn Services, Royal Women's Hospital, Neonatal Neurology, Royal Children's Hospital, Melbourne, Australia. terrie.inder@rch.org.au |
| Abstract: | Twenty-six infants with hypoxic-ischemic encephalopathy (HIE) were randomized to normothermia or to systemic hypothermia. The hypothermia group had less cortical gray matter signal abnormality on magnetic resonance imaging (MRI) (1/12 vs 7/14 infants in the normothermic group; P = .036), which may indicate differing regional benefit from systemic hypothermia. |
| Keywords: | DNG Deep nuclear gray EEG Electroencephalography HIE Hypoxic-ischemic encephalopathy MRI Magnetic resonance imaging |
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