| 血液净化对慢性肾功能衰竭患者全段甲状旁腺激素的影响 |
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| 引用本文： | 刘俊,刘志强,陶惠琴. 血液净化对慢性肾功能衰竭患者全段甲状旁腺激素的影响[J]. 南方医科大学学报, 2004, 24(2): 234-235 |
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| 作者姓名： | 刘俊 刘志强 陶惠琴 |
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| 作者单位： | 第一军医大学南方医院肾内科, 广东, 广州, 510515 |
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| 基金项目： | 收稿日期:2003-5-11。作者简介:刘俊(1962-),男,山东龙口人,1985年毕业于第一军医大学,硕士,副教授,副主任医师,电话:020-61641598 |
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| 摘 要： | 目的 研究血液灌流和/或血液透析对慢性肾功能衰竭(CRF)患者全段甲状旁腺激素(iPTH)的影响。方法 用放射免疫测定法检测40例规律血液透析患者治疗前后iPTH水平。结果 血液灌流和/或血液透析后iPTH水平均降低,但血液灌流组降低幅度大于血液透析组(P=0.031)。结论 血液灌流加血液透析能比单纯血液透析更有效地降低CRF患者iPTH水平。
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| 关 键 词： | 甲状旁腺激素 血液灌流 血液透析 肾功能衰竭 慢性 |
| 文章编号： | 1000-2588(2004)02-0234-02 |
| 修稿时间： | 2003-05-11 |
Effect of blood purification on plasma levels of intact parathyroid hormone in patients with chronic renal failure |
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| LIU Jun,LIU Zhi-qiang,TAO Hui-qin. Effect of blood purification on plasma levels of intact parathyroid hormone in patients with chronic renal failure[J]. Journal of Southern Medical University, 2004, 24(2): 234-235 |
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| Authors: | LIU Jun LIU Zhi-qiang TAO Hui-qin |
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| Affiliation: | LIU Jun,LIU Zhi-qiang,TAO Hui-qinDepartment of Nephrology,Nanfang Hospital,First Military Medical University,Guangzhou 510515,China |
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| Abstract: | Objective To study the effects of hemoperfusion and/or hemodialysis on plasma levels of intact parathyroid hormone (iPTH) in patients with chronic renal failure (CRF). Methods A total of 40 uremic patients were randomly divided into two groups to receive hemoperfusion in combination with hemodialysis (HP+HD) or exclusive hemodialysis (HD), respectively. Plasma iPTH concentration was measured by means of radio immunoassay. Results After the blood purification procedures, the patients’ plasma iPTH levels were reduced from 1 508.70±1 268.89 to 1 049.04±992.91 μg/ml (P<0.001) in HD group and from 1 600.70±1 151.15 to 745.47±785.02 μg/ml (P<0.001) in HP+HD group. Conclusion Blood purification with hemoperfusion plus hemodialysis may decrease plasma iPTH levels more efficiently than hemodialysis performed alone. |
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| Keywords: | parathyroid hormone hemoperfusion hemodialysis kidney failure chronic |
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