| 新型抗真菌药伏立康唑 |
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| 引用本文： | 沈海蓉,李中东,钟明康.新型抗真菌药伏立康唑[J].中国新药与临床杂志,2004,23(5):308-310. |
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| 作者姓名： | 沈海蓉 李中东 钟明康 |
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| 作者单位： | 复旦大学附属华山医院,临床药学研究室,上海,200040 |
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| 摘 要： | 伏立康唑 (voriconazole)是第 2代三唑类抗真菌药 ,具有抗菌谱广、抗菌效力强的特点 ,尤其对于侵袭性曲霉菌侵润所致感染疗效好。本品口服吸收好 ,病人也有很好的耐受性。本文对其药效学、药动学、药物相互作用、临床应用、不良反应等研究作一综述。
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| 关 键 词： | 抗真菌药 药动学 药理学 伏立康唑 药物不良反应 |
| 文章编号： | 1007-7669(2004)05-0308-03 |
A new antifungal agent voriconazole |
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| SHEN Hai-rong,LI Zhong-dong,ZHONG Ming-kang.A new antifungal agent voriconazole[J].Chinese Journal of New Drugs and Clinical Remedies,2004,23(5):308-310. |
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| Authors: | SHEN Hai-rong LI Zhong-dong ZHONG Ming-kang |
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| Abstract: | Voriconazole is a second-generation azole antifungal agent that shows the characters of broad-spectrum and strong antibacterial, especially has good efficacy to the infection induced by invasive aspergillus. The oral formulation has excellent bioavailability and it is well tolerated. This paper reviews the progress in the pharmacodynamics, pharmacokinetics, drug-drug interactions and clinical application, adverse reactions of voriconazole. |
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| Keywords: | antifungal agents pharmacokinetics pharmacology voriconazole adverse drug reaction |
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