腹腔镜卵巢移位术对宫颈鳞癌患者放疗前作用研究

目的探讨宫颈鳞癌患者放疗前行腹腔镜下卵巢移位术对卵巢功能的影响。方法选取2007年至2010年我院确诊为宫颈鳞癌的患者19例,其中8例术后行体内外放疗,11例术后行腔内放疗,放疗前行腹腔镜下卵巢移位（lot）术,分析手术前后及放疗后3个月、6个月、12个月患者卵巢功能的变化,以FSH、LH、E2和潮热、多汗、阴道干涩等围绝经期症状为观察指标。结果LOT手术前后患者的卵巢功能无明显变化。LOT术后放疗后3个月卵巢功能明显下降,围绝经期症状明显,放疗后6个月15例卵巢功能逐渐恢复,放疗后12个月17例卵巢功能恢复正常,2例卵巢功能减退。结论腹腔镜下卵巢移位术对患者创伤小,恢复快,护理7后就可接受放疗,对必须接受放疗的患者的卵巢功能起到提前保护的作用,对提高年轻早期宫颈鳞癌患者生活质量有重要临床意义。

Study on effect of laparoscopic ovarian transposition in patients with squamous carcinoma of cervix before radiotherapy

Objective To investigate the effects oflaparoscopic ovarian transposition on ovarian in cervi- cal squamous carcinoma before radiotherapy. Metlaods 19 cases diagnosed as squamous cell carcinoma of the cervix of in our hospital from 2007 to 2010 were selected, 8 cases underwent radical hysterectomy in vitro and ra- diotherapy, 11 cases underwent postoperative cavity after laparoscopic ovarian transposition （lot）. We analyzed o- varian function changes 3 months, 6 months and 12 months after the operation and radiotherapy, combined with menopausal symptoms, with indexes of levels of follicle stimulating hormone （FS[-I）, [uteinizing hormone （L[-I） and E2 .Resttl~ Ovarian function of 19 case had no change after LOT, after radiotherapy aH cases of ovarian function declined significantly in 3 month, ovarian function of 15 cases gradually recovered in 6 months, and 17 cases re- covered in 12 months.Conclusions Patients after laparoseopic ovarian transposition recover more quickly, and can accept radiotherapy after 7 days＇nursing. Laparoscopic ovarian transposition can protect ovarian function inadvance for patients who should accept radiotherapy, and is helpful to improve living quality of young early cervi- cal squamous carcinoma patients.