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Anti-SL-Ki antibody in a patient with fatal connective tissue overlap disease
Authors:AURORA PARODI  ANNA NIGRO  A. REBORA
Affiliation:Department of Dermatology, University of Genoa, Italy.
Abstract:A patient with photosensitivity is described who presented with an overlap syndrome combining features of systemic lupus erythematosus with a mild polymyositis and scleroderma and with symptoms of the sicca syndrome. In addition, he was anti-SSA/Ro positive and had a constellation of antibodies directed to ENA including the anti-SL-Ki antibody. The condition was fatal and he died from heart failure and respiratory insufficiency.
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