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Oxygen uptake efficiency slope as a useful measure of cardiorespiratory functional reserve in adult cardiac patients
Authors:Reizo Baba  Kazuo Tsuyuki  Yasuo Kimura  Kenji Ninomiya  Masahiko Aihara  Kunio Ebine  Nobuo Tauchi  Kenji Nishibata  Masami Nagashima
Institution:(1) Research Institute of Sports Medical Science Tokai University, 1117 Kitakaname, Hiratsuka, Kanagawa, 259-12, Japan, JP;(2) Department of Cardiology and Department of Cardiovascular Surgery, Odawara Cardiovascular Hospital, 296-1 Yahagi, Odawara, 250, Japan, JP;(3) Department of Cardiovascular Surgery, Toho University School of Medicine, 2-17-6 Ohashi, Meguro-ku, Tokyo, 153, Japan, JP;(4) Department of Pediatric Cardiology, Ohgaki Municipal Hospital, 4-86 Minaminokawa-cho, Ohgaki, 503, Japan, JP;(5) Department of Pediatrics, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466, Japan, JP;(6) Tokai University School of Physical Education, 1117 Kitakaname, Hiratsuka, Kanagawa, 259-12, Japan e-mail: babar@keyaki.cc.u-tokai.ac.jp Tel.: +81-463-581211, Fax: +81-463-50205, JP
Abstract:In this study we aimed to elucidate the validity and usefulness of the oxygen uptake efficiency slope (OUES) in the evaluation of adult cardiac patients. Cardiopulmonary exercise tests were performed on a treadmill by 50 adult patients with chronic heart failure. The OUES was calculated from data for the first 75%, 90%, and 100% of exercise duration. The OUES is derived from the following equation: O2=a× log E+b, where O2 is oxygen uptake (ml/kg/min), E is minute ventilation (l/kg/min), and the constant “a” represents OUES. We also determined the ventilatory anaerobic threshold (VAT). The correlation coefficient of the logarithmic curve-fitting model was mean (SD)] 0.986 (0.009). The OUES could be used to discriminate effectively between New York Heart Association functional classes (P < 0.001). OUES and maximum O2 were significantly correlated (r=0.78, P < 0.01). Agreement between the OUES values for the first 90%, 75%, and 100% of the exercise was excellent (intraclass correlation coefficient = 0.99). Our results suggest that OUES is applicable to adult cardiac patients as an objective, effort-independent estimation of cardiorespiratory functional reserve. Accepted: 7 September 1998
Keywords:Oxygen uptake efficiency slope  Maximal oxygen uptake  Anaerobic threshold  Exercise testing
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