Genetic polymorphism of coagulation factor XIIIB subunit in Japanese

Genetic polymorphism of coagulation factor XIIIB subunit in Japanese has been described, using thin-layer agarose gel isoelectric focusing followed by immunofixation.
Phenotypes of factor XIIIB subunit were essentially classified into three common patterns A, B and AB. It is estimated that the phenotypes are determined by two codominant alleles. A new rare variant B' has been detected in Japanese.
Gene frequencies calculated from 304 individuals showed FXIII-B^A =0.735, FXIII-B^B = 0.252 and FXIII-B^B' = 0.013, respectively. The distribution of phenotypes fitted the Hardy-Weinberg equilibrium.