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A large animal model that recapitulates the spectrum of human intervertebral disc degeneration
Authors:S.E. Gullbrand  N.R. Malhotra  T.P. Schaer  Z. Zawacki  J.T. Martin  J.R. Bendigo  A.H. Milby  G.R. Dodge  E.J. Vresilovic  D.M. Elliott  R.L. Mauck  L.J. Smith
Affiliation:2. Translational Musculoskeletal Research Center, Philadelphia VA Medical Center, Philadelphia, PA, United States;3. McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, United States;4. Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, United States;6. Comparative Orthopaedic Research Laboratory, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA, United States;5. Penn State Hershey Bone and Joint Institute, Pennsylvania State University, Hershey, PA, United States
Abstract:
Keywords:Goat  Caprine  Preclinical animal model  Disc degeneration  Chondroitinase ABC  Nucleotomy
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