A Randomized,Double‐Blind Study Comparing the Efficacy of Selenium Sulfide Shampoo 1% and Ciclopirox Shampoo 1% as Adjunctive Treatments for Tinea Capitis in Children |
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| Authors: | Catherine Chen M.D. Laine H. Koch M.D. James E. Dice Pharm.D. Kimberly K. Dempsey M.P.A. P.A.‐C. Alan B. Moskowitz M.S. Myra L. Barnes‐Eley M.P.H. Thomas W. Hubbard M.D. J.D. Judith V. Williams M.D. |
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| Affiliation: | 1. Department of Dermatology, Eastern Virginia Medical School, Norfolk, Virginia;2. Pharmacy, Children’s Hospital of the King’s Daughters, Norfolk, Virginia;3. Physician Assistant Program, Eastern Virginia Medical School, Norfolk, Virginia;4. Children’s Hospital of the King’s Daughters, Hospital Research Coordination, Norfolk, Virginia;5. Department of Pediatrics, Eastern Virginia Medical School, Norfolk, Virginia |
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| Abstract: | Abstract: Our objective was to compare the efficacy of selenium sulfide shampoo 1% and ciclopirox shampoo 1% as adjunctive treatments for tinea capitis in children. Forty children aged 1–11 years with clinically diagnosed tinea capitis were randomized to receive selenium sulfide shampoo 1% or ciclopirox shampoo 1% twice a week as adjuncts to an 8‐week course of ultramicronized griseofulvin dosed at 10–12 mg/kg/day. At weeks 2, 4, and 8, subjects returned to the clinic for evaluation and scalp cultures. Subjects then returned for follow‐up visits 4 weeks after completing treatment. Overall, by 8 weeks, 30 of 33 (90.9%) treated children demonstrated mycological cure. Selenium sulfide shampoo 1% and ciclopirox shampoo 1% were equally effective as adjunctive treatments for tinea capitis in children in our study. |
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