A Randomized,Double‐Blind Study Comparing the Efficacy of Selenium Sulfide Shampoo 1% and Ciclopirox Shampoo 1% as Adjunctive Treatments for Tinea Capitis in Children |
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| Authors: | Catherine Chen MD Laine H Koch MD James E Dice PharmD Kimberly K Dempsey MPA PA‐C Alan B Moskowitz MS Myra L Barnes‐Eley MPH Thomas W Hubbard MD JD Judith V Williams MD |
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| Institution: | 1. Department of Dermatology, Eastern Virginia Medical School, Norfolk, Virginia;2. Pharmacy, Children’s Hospital of the King’s Daughters, Norfolk, Virginia;3. Physician Assistant Program, Eastern Virginia Medical School, Norfolk, Virginia;4. Children’s Hospital of the King’s Daughters, Hospital Research Coordination, Norfolk, Virginia;5. Department of Pediatrics, Eastern Virginia Medical School, Norfolk, Virginia |
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| Abstract: | Abstract: Our objective was to compare the efficacy of selenium sulfide shampoo 1% and ciclopirox shampoo 1% as adjunctive treatments for tinea capitis in children. Forty children aged 1–11 years with clinically diagnosed tinea capitis were randomized to receive selenium sulfide shampoo 1% or ciclopirox shampoo 1% twice a week as adjuncts to an 8‐week course of ultramicronized griseofulvin dosed at 10–12 mg/kg/day. At weeks 2, 4, and 8, subjects returned to the clinic for evaluation and scalp cultures. Subjects then returned for follow‐up visits 4 weeks after completing treatment. Overall, by 8 weeks, 30 of 33 (90.9%) treated children demonstrated mycological cure. Selenium sulfide shampoo 1% and ciclopirox shampoo 1% were equally effective as adjunctive treatments for tinea capitis in children in our study. |
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