Metabolic panniculitis: alpha‐1 antitrypsin deficiency panniculitis and pancreatic panniculitis |
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Authors: | Milena J. Lyon |
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Affiliation: | Department of Dermatology, University of Illinois at Chicago, Chicago, Illinois |
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Abstract: | Panniculitis can be the initial presentation of both alpha‐1 antitrypsin deficiency and pancreatic disease. They can both present with abscess‐like draining nodules, but may present like other forms of panniculitis with erythematous nodules. It is important to consider these in the differential diagnosis of patients presenting with panniculitis. Alpha‐1 antitrypsin deficiency is a relatively common disorder mainly affecting the lungs and liver. It frequently goes undiagnosed, yet critical interventions can be made to minimize disease progression. Panniculitis associated with alpha‐1 antitrypsin deficiency can be difficult to treat. Pancreatic panniculitis occurs in less than 3% of patients with underlying pancreatic disease and is often associated with arthritis. Diagnosis and treatment of the underlying pancreatic disease is imperative. |
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Keywords: | alpha‐1 antitrypsin deficiency pancreatic panniculitis panniculitis treatment |
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