Transferrin is a growth factor for the bloodstream form ofTrypanosoma brucei |
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| Authors: | Dietmar Schell Norbert K. Borowy Peter Overath |
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| Affiliation: | (1) Abteilung Membranbiochemie, Max-Planck-Institut für Biologie, Corrensstrasse 38, W-7400 Tübingen, Germany;(2) Present address: ABION GHG, Schüzzenweg 2, W-8174 Benediktbeuern, Germany |
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| Abstract: | A method for the selective depletion of transferrin from bovine serum is presented. Bloodstream forms ofTrypanosoma brucei cannot grow in medium containing transferrin-deficient serum, whereas reconstitution with transferrin restores normal growth. We conclude that transferrin is an essential growth factor for the mammalian stage of the parasite. |
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