The effect of ingestion of ethyl alcohol, wine and beer on the myocardium of mice |
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| Authors: | G E Burch H L Colcolough J M Harb C Y Tsui |
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| Institution: | 1. From the Department of Medicine, Tulane University School of Medicine, New Orleans, La. U.S.A.;2. From the Charity Hospital of Louisiana, New Orleans, La. U.S.A. |
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| Abstract: | Histologic and ultrastructural changes in the myocardium of mice consuming various concentrations of pure ethanol, beer and wine as their sole liquid intake for 4 to 10 weeks are described. Ultrastructural alterations were seen in the sarcoplasmic reticulum, myofilaments and intercalated discs. The changes were minor but discernible. The pathogenesis of these changes is discussed in terms of a possible direct toxic effect of alcohol on the myocardium. |
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