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48例肺类癌患者的临床特征及预后分析
引用本文:王莹,张同梅,钱哲,董宇杰,高远,刘赞,胡范彬,李宝兰. 48例肺类癌患者的临床特征及预后分析[J]. 癌症进展, 2019, 17(7): 851-855
作者姓名:王莹  张同梅  钱哲  董宇杰  高远  刘赞  胡范彬  李宝兰
作者单位:首都医科大学石景山教学医院/北京市石景山医院肿瘤科,北京,100043;首都医科大学附属北京市胸科医院/北京市结核病胸部肿瘤研究所综合科,北京,1011490;首都医科大学附属北京市胸科医院/北京市结核病胸部肿瘤研究所 病理科,北京,1011490
摘    要:目的分析肺类癌(PC)患者的临床资料,提高对PC的认识。方法收集48例PC患者的临床资料,并对性别、年龄、吸烟史、病理类型、肿瘤大小、N分期、远处脏器转移和TNM分期等与PC患者预后的关系进行分析。结果 48例PC患者中,典型类癌(TC)30例,不典型类癌(AC)18例;临床表现以咳嗽、痰中带血为主;37例患者行手术治疗,11例患者行姑息性放化疗或对症支持治疗。48例PC患者的1、3、5年生存率分别为87.5%、83.3%、77.1%。单因素分析结果显示,不同病理类型、N分期、远处脏器转移、TNM分期PC患者的中位总生存期比较,差异均有统计学意义(P﹤0.05);多因素分析结果显示,TNM分期是PC患者总生存期的独立影响因素(P﹤0.01)。结论 PC的临床表现缺乏特异性,确诊主要依据术后病理。手术切除为PC的主要治疗手段,TNM分期是PC患者预后的独立影响因素。术后辅助化疗在PC治疗中的地位有待进一步确认。

关 键 词:肺神经内分泌肿瘤  肺类癌  典型类癌  不典型类癌  临床特征  预后因素

Clinical characteristics and prognostic analysis of 48 cases of pulmonary carcinoid
WANG Ying,ZHANG Tongmei,QIAN Zhe,DONG Yujie,GAO Yuan,LIU Zan,HU Fanbin,LI Baolan. Clinical characteristics and prognostic analysis of 48 cases of pulmonary carcinoid[J]. Oncology Progress, 2019, 17(7): 851-855
Authors:WANG Ying  ZHANG Tongmei  QIAN Zhe  DONG Yujie  GAO Yuan  LIU Zan  HU Fanbin  LI Baolan
Affiliation:(Department of Oncology,Shijingshan Teaching Hospital of Capital Medical University/Beijing Shijingshan Hospital,Beijing 100043,China;Department of General Medicine,Affiliated Beijing Chest Hospital of Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute,Beijing 101149,China;Department of Pathology,Affiliated Beijing Chest Hospital of Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute,Beijing 101149,China)
Abstract:WANG Ying;ZHANG Tongmei;QIAN Zhe;DONG Yujie;GAO Yuan;LIU Zan;HU Fanbin;LI Baolan(Department of Oncology,Shijingshan Teaching Hospital of Capital Medical University/Beijing Shijingshan Hospital,Beijing 100043,China;Department of General Medicine,Affiliated Beijing Chest Hospital of Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute,Beijing 101149,China;Department of Pathology,Affiliated Beijing Chest Hospital of Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute,Beijing 101149,China)
Keywords:pulmonary neuroendocrine tumor  pulmonary carcinoid  typical carcinoid  atypical carcinoid  clinical characteristic  prognostic factor
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