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Simultaneous Analysis of Thirteen Bioactive Components in Evodia rutaecarpa and Its Varieties by HPLC-DAD-MS |
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| Authors: | XU Hai-yu ZHANG Tie-jun XIAO Xue-feng ZHAO Ping LIU Chang-xiao XU Jun |
| Affiliation: | 1. Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China;The National Laboratory of Pharmacodynamics and Pharmacokinetics,Tianjin Institute of Pharmaceutical Research,Tianjin 300193,China 2. Tianjin Engineering Laboratory of Quality Control Techniques for TCM,Tianjin Institute of Pharmaceutical Research,Tianjin 300193,China 3. Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China 4. The National Laboratory of Pharmacodynamics and Pharmacokinetics,Tianjin Institute of Pharmaceutical Research,Tianjin 300193,China |
| Abstract: | Objective To control the quality of Evodia rutaecarpa better.Methods An HPLC-DAD-MS/MS method was established for the rapid and efficient identification of bioactive constituents and for simultaneous quantitative analysis of four bioactive ingredients including evodiamine,rutaecarpine,dehydroevodiamine,and evodin in E.rutaecarpa,which was applied to evaluating eight samples of E.rutaecarpa and its varieties from different areas.Results Thirteen potentially bioactive constituents including one flavonoid glyc... |
| Keywords: | dehydroevodiamine Evodia rutaecarpa evodiamine evodin HPLC-DAD-MS rutaecarpine |
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