顺氯氨铂、丝裂霉素和平阳霉素联合治疗食管癌41例结果

1986年7月～1987年12月采用顺氯氨铂、丝裂霉素、平阳霉素联合化疗治疗食管癌41例。完全缓解6例(14.6％),部分缓解17例(41.5％),微效9例(21.9％),稳定4例(9.8％),无效5例(12.2％)。完全缓解和部分缓解率(CR+PR)56.1％,总有效率(CR+PR+MR)78％,中位生存期7个月(2—32个月)。毒副反应有食欲减退,恶心、呕吐、脱发、发热、骨髓抑制.

THE RESULTS OF 41 CASES ESOPHAGEAL CARCINOMA WITH COMBINATION CHEMOTHERAPY OF CISPLATIN,MITOMYCIN, AND PINGYANGMYCIN

From July 1988 to December 1987, 1st Affitiated Hospital of Henan Medical University, forty-one patients with esophageal carcinoma were treated by combination chemotherapy of cisplatin,mitomycin,and pingyangmycin. The treatment results showed that 8 cases (14,6%)of"complete remission ,9 cases (21.9%) of minimal response, 4 cases (9.8%) of stable and 5 cases (12.2%) of progression. The complete and partial remission rate (CR+PR) was 56.1% and the total response rate (CR+PR+MR) 78%.The median survival was 7 months (range 2-32 months).The toxicities seen were anorexia,nausea,vomiting, alopecia, hyperpyraxia, and mid myelodelodepressiof.