急性心肌梗死早期静脉及口服应用美托洛尔对心率变异性的相关研究

目的:探讨急性心肌梗死(AMI)早期静脉及口服应用美托洛尔对心率变异性(HRV)的影响。方法:将我院2012年1月-2012年l2月收治的AMI患者100例随机分为对照组和观察组各50例,对照组予常规药物治疗,观察组在对照组治疗的基础上,予静脉及口服应用美托洛尔治疗4周,比较治疗前、后两组HRV的变化。结果:与治疗前比较,治疗后两组HRV指标均明显改善,但观察组的改善更明显,P均0.05。结论:早期静脉及口服应用美托洛尔可改善AMI患者的HRV,使失衡自主神经改善。

Related Research of Heart Rate Variability Patients with Acute Myocardial Infarction Treated by Metoprolol Early Intravenous then Oral

Objective： To investigate the effect of early intravenous then oral using of metoprolol on heart rate variability（HRV） for patient with acute myocardial infarction（AMI）. Methods： 100 patients with AMI from Jan 2012 to Dec 2012 were randomly divided into observation group and control group , each group was 50 cases. The patients in observation group were treated by early intravenous then oral using of metoprolol based on control group treated by conventional drug therapy for 4 weeks. The HRV were compared between the two groups. Results： Compared with the before treatment,the HRV were significantly improved after the treatment 4 weeks in the both groups, but HRV in observation group was significantly better than that in ontrol group after the treatment , both P ＆lt; 0.05. Conclusion：Early intravenous then oral using of metoprolol can effectively improve HRV of patients with AMI and improve the imbalance autonomic nervous.