| 血清GPDA-F/ALT、GGT-II与AFP同步检测对肝细胞癌的诊断价值 |
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| 引用本文： | 季颖林,倪润洲,黄介飞,肖明兵,李立人,孟宪镛.血清GPDA-F/ALT、GGT-II与AFP同步检测对肝细胞癌的诊断价值[J].南通医学院学报,2003,23(4):390-390. |
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| 作者姓名： | 季颖林 倪润洲 黄介飞 肖明兵 李立人 孟宪镛 |
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| 作者单位： | 1. 南通医学院第二附属医院消化内科,南通226001
2. 南通医学院附属医院消化内科 |
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| 摘 要： | 目的 :探讨甘氨酰脯氨酸二肽氨基肽酶 (GPDA-F/ALT)、r-谷氨酰转肽酶 (GGT- )和甲胎蛋白 (AFP)联合检测对肝癌的诊断价值。方法 :对 10 8例肝癌和 130例良性肝病患者进行了 GPDA-F/AL T、GGT-II和 AFP3项指标联合检测 ,分析这些指标对肝癌的互补诊断价值。结果 :肝癌患者 GPDA-F/ALT、GGT-II和 AFP3项指标均高于良性肝病 ;GPDA-F/ALT与GGT-II和 AFP之间无相关性 ;3项指标同步检测可明显提高肝癌的诊断敏感性。结论 :GPDA-F/ALT、GGT-II和 AFP3项指标对肝癌有互补诊断价值 ,联合检测能提高肝癌的诊断水平。
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| 关 键 词： | 原发性肝细胞癌 甘氨酰脯氨酸二肽氨基肽酶 γ-谷氨酰转肽酶 甲胎蛋白 |
| 文章编号： | 1000-2057(2003)04-0390-02 |
| 修稿时间： | 2003年5月22日 |
Simultaneous determination of serum GPDA-F/ALT,GGT-II and AFP for the diagnosis of primary hepatic carcinoma |
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| JI Yinglin,NI Runzhou,HUANG Jiefei,et al.Simultaneous determination of serum GPDA-F/ALT,GGT-II and AFP for the diagnosis of primary hepatic carcinoma[J].ACTA Academiae Medicinae Nantong,2003,23(4):390-390. |
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| Authors: | JI Yinglin NI Runzhou HUANG Jiefei |
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| Abstract: | Objective:To explore the value of GPDA-F/ALT, GGT-II and AFP in the diagnosis of primary hepatic carcinoma (PHC).Methods:GPDA-F/ALT, GGT-II and AFP were detected and their complementary diagnostic value to PHC was analyzed.Results:All of GPDA-F/ALT, GGT-II and AFP were significantly higher in PHC than in benign liver diseases. GPDA-F/ALT did not correlate with GGT-II and AFP. Simultaneous measurement of these three indices significantly improved diagnostic sensitivity to PHC.Conclusion:GPDA-F/ALT, GGT-II and AFP were complementary to PHC, and combined determination of these indices could improve the diagnosis of PHC. |
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