| 国产安吖啶联合治疗急性白血病30例临床观察 |
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| 引用本文： | 赵耀中,卞寿庚,梁彦,薛艳萍,孟庆祥,秦铁军,郭亚林,刘兵诚.国产安吖啶联合治疗急性白血病30例临床观察[J].白血病．淋巴瘤,1997(2). |
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| 作者姓名： | 赵耀中 卞寿庚 梁彦 薛艳萍 孟庆祥 秦铁军 郭亚林 刘兵诚 |
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| 作者单位： | 中国医学科学院中国协和医科大学血液学研究所 |
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| 摘 要： | 采用国产安吖啶（ｍ－ａｍｓａｃｒｉｎｅ，ＡＭＳＡ）联合方案治疗急性白血病（ＡＬ）３０例；急性淋巴细胞白血病（ＡＬＬ）６例，急性非淋巴细胞白血病（ＡＮＬＬ）２４例；初治２１例，复治９例。总的ＣＲ率为７６．７％；ＡＬＬ的ＣＲ率为６６．６％，ＡＮＬＬ的ＣＲ率为７９．２％，初、复治病例的ＣＲ率分别为８０．９％、６６．７％。主要毒性为骨髓抑制，其次为脱发、食欲下降、恶心、呕吐、口腔粘膜炎、静脉炎等。
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| 关 键 词： | 安吖啶 急性白血病 |
ABSERVATION OF COMBINED DOMESTIC AMSACRINE FOR TREATMENT OF 30 LEUKEMIA |
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| Zhao Yaozhong,Bian Shougen,Liang Yan,et al Haemotologic Institute Attached China Medical Acadmy,.ABSERVATION OF COMBINED DOMESTIC AMSACRINE FOR TREATMENT OF 30 LEUKEMIA[J].Journal of Leukemia & Lymphoma,1997(2). |
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| Authors: | Zhao Yaozhong Bian Shougen Liang Yan Haemotologic Institute Attached China Medical Acadmy |
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| Abstract: | Patients with acute leukemias, 6 acute lymphoblastic leukemias(ALL) and 24 acute nonlymphoblastic leukemias(ANLL), were treated with combination chemotherapy including domestic Amascrine(m AMSA). The total CR rates was 76.7%(66.6% in ALL, 79.2% in ANLL). The CR rates of previously untreated and treated patients were 80.9% and 66.7%, respectively. The chief toxicity was myelosuppression, aloecia, nausea, vomiting, mucositis and phlebitis. |
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| Keywords: | Amsacrine Acute leukemia |
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