| 利培酮与氯丙嗪治疗精神分裂症对心电图的影响 |
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| 引用本文： | 董秀凤,张玉胜,吴丽荣. 利培酮与氯丙嗪治疗精神分裂症对心电图的影响[J]. 药物流行病学杂志, 2003, 12(5): 241-242 |
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| 作者姓名： | 董秀凤 张玉胜 吴丽荣 |
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| 作者单位： | 滨州市人民医院,山东,滨州,256610 |
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| 摘 要： | 目的 :了解和比较利培酮与氯丙嗪对心电图的影响。方法 :对服用利培酮及氯丙嗪的精神分裂症患者分别定期心电图检查 ,时间为服药后 2、4周。结果 :利培酮组和氯丙嗪组出现异常分别为 11.5 %和 4 2 .5 % ,两者有显著性差异 (P <0 .0 5 )。结论 :利培酮对心电图影响明显低于氯丙嗪。
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| 关 键 词： | 利培酮 氯丙嗪 药物治疗 精神分裂症 心电图 药物不良反应 |
The Effects of the Treatment of Patients with Risperidone and Chlorpromazine on Electrocardiogram(ECG) |
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| Dong Xiufeng,Zhang Yusheng,Wu Lirong Binzhou City People''s Hospital,Shandong,P. R. China. The Effects of the Treatment of Patients with Risperidone and Chlorpromazine on Electrocardiogram(ECG)[J]. Chinese Journal of Pharmacoepidemiology, 2003, 12(5): 241-242 |
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| Authors: | Dong Xiufeng Zhang Yusheng Wu Lirong Binzhou City People''s Hospital Shandong P. R. China |
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| Affiliation: | Dong Xiufeng,Zhang Yusheng,Wu Lirong Binzhou City People's Hospital,Shandong 256610,P. R. China |
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| Abstract: | Objective: To study the effect of the treatment of patients with risperidone and chlorpromazine on ECG respectively. Methods: The patients were treated with risperidone and chlorpromazine, and ECG were regularly recorded in 2 to 4 weeks separately. Result: The abnormal rate was 11.5% in the risperidone group and that of chlorpromazine, 42.5% . The significant differences were found between the two groups ( P < 0.05 ). Conclusion: The effect of risperidone on the abnormal ECG was lower than that of chlorpromazine. |
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| Keywords: | Risperidone Chlorpromazine ECG Adverse drug reaction |
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