青年乳腺癌63例诊治分析

目的 :探讨青年乳腺癌 (年龄≤ 35岁 )的临床特点及预后。方法 :回顾性分析 35岁以下青年乳腺癌 63例的临床特点及预后 ,并随机抽取同期非青年乳腺癌 70例作为对照 ,比较两组患者临床特点及预后之间的差异。结果 :63例中 ,病程为 3d至 35月 ,平均 1 1 .3月 ;病理分型以浸润性癌为主 ,占 93.7% ( 5 9/63) ;41例有腋下淋巴结转移 ,占 65 .1 % ;有1 0例为妊娠、哺乳期患者 ;随访率 1 0 0 % ,青年组 3年、5年生存率分别为 79.4%、5 8.7% ;而对照组分别为 92 .7%、77.1 %。青年组根治术后 3年、5年复发转移率分别为 35 .0 %、5 5 .0 % ;而对照组分别为 1 5 .9%、31 .9% ,两组预后存在明显差异 ( P<0 .0 5 )。结论 :青年乳腺癌病程较长 ,浸润性癌为主 ,淋巴结转移率高 ,加之合并妊娠、哺乳 ,预后较差

Clinical analysis of breast cancer in young women(a report of 63 cases)

Objective:To study the clinical characteristics and prognosis of breast cancer in young women.Methods:The study was reviewed and sorted out original data, looked up along with clinicopathologic conclusion. The study group had 63 cases within 35 years old, and the control group had 70 cases above 35 years old.Results:The progress of the study group was 3 days to 35 months,averaging out to 11.3 months. The invasive ductal cancer dominated in pathologic histology in the young people group. There were 41 cases with lymphatic metastasis and 10 cases in cyesis or lactation in study group. The 3- year survival rate and 5- year survival rate of the study group were 79.4% and 58.7% respectively, while that of the control group were 92.7% and 77.1%. The 3- year relapse rate and 5- year relapse rate of the study group were 35.0% and 55.0% respectively, while that of the control group were 15.9% and 31.5%. There was statistically significant difference between two groups(P<0.05).Conclusion:Breast cancer of young people had worse prognosis because of invasive pathologic histology, lymphatic metastasis and long progress.