银杏叶片对高原人体运动血液流变学的影响

目的 探讨银杏叶片、红景天和酪氨酸对高原人体力竭运动血液流变学的影响。方法 对进驻海拔3700m高原半年的30名健康青年随机分为银杏叶片组、红景天组和酪氨酸组，每组10人。在服药前、服药第15天分别进行运动至力竭，分别检测血中红细胞压积(HCT)、血液粘度(ηb)、血浆粘度(ηp)、还原粘度(ηr)、红细胞刚性指数(IR)、红细胞变形系数(TK)、红细胞聚集系数(VAI)及血栓形成系数(TFL)。结果 服药前力竭运动后较安静时HCT、ηb、ηp、ηr、IR、TK、VAL、TFL均升高(P＜0．05或P＜0．01)。服药后力竭运动后较安静时银杏叶片组和酪氨酸组ηr、Tk增高(P＜0．05或0．01)；红景天组ηp、ηr、TK增高(P＜0．05)，其余均无统计学差异(P＞0．05)。服药后较服药前银杏叶片组HCT、ηb、ηp、ηr、IR、TK、VAI、TEL均降低(P＜0．05或0．01)；红景天组和酪氨酸组ηb、ηp、ηr、IR、TK、VAI、TFL降低(P＜0．05或0．01)，HCT无统计学差异(P＞0．05)。银杏叶片组、酪氨酸组和红景：天组之间比较血液流变学指标均无统计学差异(P＞0．05)。结论 三种药物均具有改善组织微循环及血液流变性的作用，使红细胞变形能力增强，血液粘度下降，血流速度增加。

Effects of Folium Ginkgo Extract on Hemorrheology before and after exercise at high Altitude

Objective To study the effects of folium ginkgo extract on hemorrheology before and after exercise at high altitude. Methods The 30 healthy youth were randomly divided into 3 groups (folium ginkgo extract,rholida and tyrosine;) ,who have stayed at high altitude(3700m)for 6 months. To determine their HCT,nb,np,nr,IR,TK,VAI and TFL before and after taking drugs for 15 days, and after exhaustion-exercise. Result All those indexes were increased after exhaustion-exercise (P < 0.05 or 0.01). After taking drugs for 15 days,the nr and TK were increased in folium ginkgo extract and tyro-sine group( P < 0.05 or F<0.01), the rholida group' s np ,nr and TK were increased( P < 0.05). Compared with the before taking drugs,all those indexes in three drug groups were decrease(P<0.05 or P <0.01),but the HCT is no statistics meaning in rholida and tyrosine group (P >0.05) .Conclusion Folium ginkgo extract,rholida and tyrosine could improve the tissue microcircultion and hemorrheology, increase the erythrocyte changeableness and decrease blood viscosity at altitude.