尿毒症合并急性冠脉综合征患者冠脉介入诊疗安全性及疗效观察

目的 探讨尿毒症并接受规律的血液及腹膜透析的急性冠脉综合征（ACS）患者进行冠状动脉（简称冠脉）介入治疗的安全性及疗效。方法回顾分析从2010年5月至2013年3月已维持规律透析并因ACS在我院住院连续的10例患者，均在适当水化和透析基础上，应用非离子型等渗造影剂进行冠脉造影检查及经皮冠脉介入术（PCI）。结果7例（70％）成功植入支架，2例行外科搭桥手术，1例冠脉造影术后第6天等待外科手术时发生脑出血死亡。术后监测肾功能无进一步恶化，临床随访期间无主要心脏不良事件发生。结论对血液透析患者行冠脉造影及介入治疗是安全可行的，临床疗效良好。

Safety and efficacy of coronary intervention in patients with uremia and ACS

Objective To probe the safety and efficacy of coronary artery intervention treatment for acute coronary syndrome （ACS） in uremia patients on regular blood or peritoneal dialysis. Methods Ten maintenance dialysis patients hospitalized in our hospital because of ACS from May 2010 to March 2013 were retrpspectively analyzed. The nonionie isotonic contrast agent was used during coronary angiography and percutaneous coronary intervention （PCI）. Results Seven eases （70%） had successful stent placement, 2 eases （20%） underwent bypass surgery, 1 case died of cerebral hemorrhage 6 days after coronary angiography at the time of waiting for surgery. There was no further deterioration in renal function after the treatment. No major adverse cardiac events occurred during clinical follow - up. Conclusion Coronary arteriography and intervention treatment is safe and feasible for ACS in hemodialysis patients and the clinical effect is good.