蒙药那如-3抗炎镇痛作用的实验研究 |
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引用本文: | 白梅荣,图雅,巴根那,包晓华,萨出日拉.蒙药那如-3抗炎镇痛作用的实验研究[J].中国民族医药杂志,2010,16(4):35-37. |
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作者姓名: | 白梅荣 图雅 巴根那 包晓华 萨出日拉 |
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作者单位: | 内蒙古民族大学,内蒙古,通辽,028041 |
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摘 要: | 目的:研究蒙药那如-3的镇痛、抗炎作用。方法:采用热板刺激、冰醋酸刺激小鼠扭体、小鼠耳肿胀、大鼠棉球致肉芽肿及角叉菜胶致大鼠足肿胀等方法研究蒙药那如-3的镇痛及抗炎作用。结果:蒙药那如-3能明显抑制大鼠足跖肿胀度(P0.05),明显抑制二甲苯致小鼠耳廓肿胀(P0.01),抑制棉球埋藏引起的慢性肉芽肿(P0.01);延长小鼠疼痛反应时间(P0.05),减少小鼠扭体次数(P0.01)。结论:蒙药那如-3具有显著的镇痛、抗炎作用。
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关 键 词: | 蒙药那如-3丸 抗炎 镇痛 |
Analgesic and Anti -inflammation Effect of Naru -3 of Mongolian Medicine |
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Institution: | Bai Meirong, Tu Ya, Bagenna, Bao Xiaohua, Sachurila ( College of Mongolian Medicine and Pharmacy, Inner Mongolia University for Nationalities, Tongliao 028041, China) |
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Abstract: | Objective :To observe the analgesic action and anti -inflammation effect of Naru- 3 of mongolian medicine. Methods: The analgesic action and anti - inflammation effect of Naru - 3 of mongolian medicine were observed by mouse hot - plate test, mouse acetic -acid -in -duced twisting test, mouse pinna swelling induced by xylene, rat proliferation of granuloma led by im- planting cotton pellet was selected, and rat pedal swelling test induced by earragecnin. Results : Naru - 3 of mongolian medicine reduced the pedal swelling of rats (P 〈 0.05 ), obviously inhibited the swelling of mouse pinna induced by xylene (P 〈 0.01 ), significantly depressed the increase of proliferation of granuloma led by implanting cotton pellet ( P 〈 0.01 ), creased pain threshold in mice ( P 〈 0.05 ), inhibited twisting response of mice obviously( P 〈 0.01 ). Conclusion: Naru - 3 of mongolian medicine has certain analgesic action and anti -inflammation effect. |
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Keywords: | Naru - 3 of mongolian medicine Analgesic action Anti - inflammation effect |
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